Jonathan Weissman is professor at the Whitehead Institute of MIT and an investigator of the Howard Hughes Medical Institute. Formerly, he was vice chair of the Department of Cellular & Molecular Pharmacology at the University of California, San Francisco and served as the co-director of the Innovative Genomics Institute (IGI) of Berkeley and UCSF and on the President’s Advisory Group for the Chan Zuckerberg Biohub. He also is the chairman of the scientific advisory board for the Stowers Institute and serves on the scientific advisory board for Amgen and the Helen Hay Whitney Foundation. Jonathan is widely recognized for building innovative tools for broadly interrogating the organizational principals of biological systems. These include ribosome profiling for globally monitoring protein translation and the development of CRISPRi/a to enable fine-tuned modulating human gene expression at genome scale. He has received the Irving Sigal Young Investigator Award from the Protein Society, the Raymond and Beverly Sackler International Prize in Biophysics, the National Academy of Sciences Award for Scientific Discovery, and the Keith R. Porter Lecture Award from the American Society for Cell Biology. Jonathan is a member of the National Academy of Sciences.